Browsing by Author "Ratchada Viriyapong"

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    Mathematical model of measles transmission dynamics using real data from Nigeria
    (Informa UK Limited, 2022-05-25) Olumuyiwa James Peter; Mayowa M. Ojo; Ratchada Viriyapong; Festus Abiodun Oguntolu
    Measles is a highly contagious and life-threatening disease caused by a virus called morbillivirus, despite the availability of a safe and cost-effective vaccine, it remains a leading cause of death, especially in children. Measles spreads easily from person to person via infected people's coughs and sneezes. It can also be transmitted through direct contact with the mouth or contaminated surfaces. To have a better knowledge of measles epidemiology in Nigeria, we develop a deterministic mathematical model to study the transmission dynamics of the disease in the population. The boundary of the model solution is performed, both equilibrium points are calculated, and the basic reproduction number ℛ0 is determined. We have proved that when ℛ0<1, the disease-free equilibrium point is both locally and globally stable. When ℛ0>1, the endemic equilibrium point exists and is stable if it satisfies Routh–Hurwitz criteria. We demonstrate the model's effectiveness by using a real-life application of the disease spread in Nigeria. We fit the proposed model using available data from Nigeria Center for Disease Control (NCDC) from January to December 2020 to obtain the best fit, this help us to determine the accuracy of the proposed model's representation to the real-world data. We investigate the impact of vaccination rate and hospitalization of infected individuals on the dynamics of measles in the population. The result shows that the combined control strategies reduce the peak of infection faster than the single control strategy.
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    Stability and optimal control analysis of an SCIR epidemic model
    (SCIK Publishing Corporation, 2020-10-16) Olumuyiwa James Peter; Ratchada Viriyapong; Festus Abiodun Oguntolu; Pensiri Yosyingyong; Helen Olaronke Edogbanya; Michael Oyelami Ajisope
    In this paper, we proposed a deterministic model of SCIR governed by a system of nonlinear differential equations. Two equilibria (disease-free and endemic) are obtained and the basic reproduction number R0 is calculated. If R0 is less than one, then the disease-free equilibrium state is globally stable i.e. the disease will be eradicated eventually. However, when R0 is greater than unity, the disease persists and the endemic equilibrium point is globally stable. Furthermore, the optimal control problem is applied into the model. The focus of this study is to determine what control method can be implemented to significantly slow the incidence of the epidemic disease, therefore we take into account various possible combinations of such three controls which are prevention via proper hygiene, screening of the infected carriers which enable them to know their health conditions and to go for early treatment and treatment of the infected individuals. The possible strategies of using combinations of the three controls on the spread of the disease, one at a time or two at a time is also discussed. Our numerical analysis of the optimal approach suggests that the best method is to incorporate all three controls in order to control the disease epidemic.