Mathematical Modelling for the Effect of Malaria on the Heterozygous and Homozygous Genes
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Date
2018-03-25
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Publisher
ICAPTA
Abstract
This paper models the effect of malaria on the homozygous for the normal gene (AA),
heterozygous for the sickle cell gene (AS), and homozygous for the sickle cell gene (SS) using the
first-order ordinary differential equation. The Diseases Free Equilibrium (DFE) was obtained
and used to compute the basic reproduction Number Ro. The local stability of the (DFE) was
analyzed.
Description
Keywords
heterozygous, homozygous, sickle cell diseases, plasmodium, genotype