Mathematical Modelling for the Effect of Malaria on the Heterozygous and Homozygous Genes
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Date
2019-03-29
Journal Title
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Publisher
6th International Conference on Mathematical Analysis and Optimization: Theory and Applications (ICAPTA 2019)
Abstract
This paper models the effect of malaria on the homozygous for the normal gene (AA),
heterozygous for sickle cell gene (AS) and homozygous for sickle cell gene (SS) using the
first order ordinary differential equation. The Diseases Free Equilibrium (DFE) was obtained
and used to compute the basic reproduction Number Ro. The local stability of the (DFE) was
analyzed.
Description
Keywords
heterozygous, homozygous, sickle cell diseases, plasmodium, genotype